
Lactiplantibacillus plantarum CCFM602 features a short generation time and high survival rate under in‑vitro simulated gastric acid and small‑intestinal fluid conditions. Its survival rate in gastric fluid reaches 88 %, and 93 % in intestinal fluid. It exhibits excellent adhesion to human HT‑29 cells at 30 cells per host cell, with low antibiotic resistance. It can significantly restore ampicillin‑induced gut microbiota dysbiosis in mice, effectively alleviate antibiotic‑associated diarrhea and improve intestinal function.